I have gotten a lot of questions regarding Gynomastia lately, what is it and how to take care of it.
Clinically, gynomastia, is defined by the presence of a rubbery or firm mass extending concentrically from the nipples and extending out to the rest of the breast tissue. Men who start experiencing this problem complain of pain and tenderness around the nipple area, and some may even have a discharge from the nipples.
Gynomastia has two causes from a PH/DS aspect, one is the amount of estrogen in the body. The other is the amount of progesterone or progestins with in the body.
Now the estrogen has been taken care of for a few years with the use of estrogen inhibitors--Arimidex, Femara, and Aromasin--literally inhibit aromatase. Without aromatase, there is no conversion of Testosterone to estrogen. Personaly speaking, I'm not sure why people would not use these in moderation, if the worry of gynomastia was ever a concern.
Prolactin and progesterone do not have direct effects on each other.
Estrogen and Progesterone do. Prolactin and testosterone have direct effects on each other.
Elevated estrogen levels means a decrease in progesterone levels and vice versa.
Elevated Prolactin levels means lowered testosterone/dopamine levels and vice versa
When prolactin levels are increased, testosterone and dopamine levels are reduced. With that testosterone decrease, your body reduces the amount of estrogen being produced as well which results in an increase of progesterone(this is why most catagorize progest./prolactin together)
Now if a prolactin inhibitor is introduced, your test/dopamine levels will raise. This raise in testosterone can trigger your body to produce estrogen to compensate this increase. At this point progesterone is decreased to balance out the estrogen/progesterone ratio.
So in the case of a Deca cycle. Deca is administered, and prolactin increases(common with Deca). With that prolactin increase, the persons testosterone is lowered(along with dopamine). The lowered testosterone triggers a decrease in estrogen production which raises progesterone.
This is the reason why it is very important to have an anti-estrogen and prolactin inhibitor when partaking in a cycle that increases prolactin such as Decca. If you lower that prolactin, your test levels will increase there by increasing estrogen production.
So how do we control prolactin? The safest course to help control progetin, is Vit B6 at 200 to 400mg every day through out your cycle and pct. Also there has been a few meds that have come up pretty recently-
Bromocriptine
Pergolide(Permax)
Cabergoline
Quinagolide
Terguride
Any of these should be researched before administration and I am not suggesting these. Just listing