5A-Laxogen Rx – Anabolic Building Block
MAIN BENEFITS OF 5A-Laxogen Rx
• Promotes Muscle Growth
• Increases Protein Synthesis
• Increases Endurance
• Non-Hormonal Compound
• Safe for Males & Females
5a-Hydroxy Laxogenin was discovered in 1996 and shown to have an anabolic/androgenic ratio similar Anavar, but without the side effects of liver toxicity or testing positive for steroidal therapy. Athletes claim to have seen strength increases in 3-5 days, and muscle mass increases in 3-4 weeks.
“Laxogenin does indeed have some pretty profound anti-inflammatory effects. In addition to being able to be synthesized from Diosgenin, it is a component of smilax sieboldii.”
“Laxogenin is a steroidal sapogenin isolated from Smilax sieboldi. As a spirostanic analogue of the brassinosteroid – teasterone, Laxogenin is noted for it’s growth promoting activity [in plants]. It has also been demonstrated to aquire [cytotoxic] properties however, to what degree, I am not sure. In contrast, Laxogenin was demonstrated to aquire antitumor-promoting activity in a two-stage lung carcinogenesis experiment.”
“The best (published) study can be found in the journal Phytochemistry, 1971, vol. 10, pp 1339-1346. Again in 1989, same journal vol. 28, no. 9 pp 2509-2511 (laxogenin acetate). There is reference going back to 1965 in Chem. Pharm. Bull. 13(5), pp. 545-550 (laxogenin).
It was Syrov’s paper of 1976 though, appearing in Farmakol, Toksikol that really sparked my interest. The paper is entitled, “An Experimental Study on the Anabolic Activities of 6-keto Derivatives of some natural sapogenins”.
It details the 4 sapogenins (referred to as compounds 1-4 in the Soviet Union) and gives source material, results of the classic steroid model (levator ani studies) and mentions other clues critical to their use. Most of these compounds can be derived from Diosgenin (so can testosterone).
Laxogenin appears closest to Compound 2, the most desirable of these. Thermo includes it as 25R in their formulation and I very much wish it were available as a standalone. I can tell you from experience that when you get the right Laxogenin, it for sure delivers on the recovery, anti-inflammatory etc. side of things and is a superb regenerative agent.
Take one (1) or two (2) capsules up to 3 times daily with food.