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Prohormones – Topical vs. Oral Administration
Although comparable to oral-dosage forms in efficacy, topical creams have numerous advantages over oral forms. First, topical administration avoids the first-pass effect of metabolism associated with the oral route. Therefore, topical administration allows for much higher and improved bioavailability. Second, topical administration allows prolonged release of prohormone compounds, which can improve adherence. Third, topical administration minimizes adverse effects due to lower prohormone peak concentrations. Prohormones are very effectively removed by the liver when taken orally. This means that much higher doses, ten to twenty times higher, must be taken when administering prohormones orally, as compared to topical administration that avoid the first pass effect of the liver.
100mg R-DHEA (Per 2 Pumps)
- 100 Pumps Per Bottle
- Suggested Dose is 2 Pumps Daily
R-DHEA is known as “Reduced DHEA” because it is a 5a-reduced metabolite of DHEA. It’s more commonly referred to as Androsterone. This naturally occurring hormone cannot convert to testosterone, but instead converts to the dihydrotestosterone (DHT). Similar to testosterone, DHT is responsible for masculine traits such as aggression, sex drive, and physical strength. However, because DHT cannot convert to estrogen, it also helps reduce fat storage and water retention, making it an excellent steroid for increasing muscular hardness and vascularity.
R-DHEA will stack well with 4-DHEA as it may help reduced water retention from under the skin, thus creating a “dry” and hard appearance. R-DHEA also has moderate anabolic properties thus allowing it to help enhance lean muscle gains.
Strength gains may also be noticeable with R-DHEA due to its strong androgenic effect which will activate the central nervous system and increase muscular power.This will increase explosive power with minimal body weight increase. The increased aggression is typically a welcomed benefit, which manifests as increased confidence and an “alpha male” feeling in sexual and social activities. The strong androgenic action from R-DHEA may also help support libido and erection hardness. This makes R-DHEA useful to help counter the sexually suppressive effects from other steroids. The powerful androgenic effect will also block estrogenic effects, and help prevent (and reverse) gyno.
R-Andro Cream Topical Delivery System
- Dimethyl Isosorbide (DMI) – is a high purity solvent and carrier which offers a safe, effective delivery enhancement mechanism for the active ingredients in R-Andro Cream.
- Ethoxydiglycol – is a cosmetic grade solvent that conforms to the current USP/NF monographs. Ethoxydiglycol is particularly appropriate for skin care preparations where it acts as an excellent solvent and carrier.
- Propylene glycol – is an organic compound that is used 2 primary reasons. First, it has the traits of a humectant; it is able to absorb and help the skin retain moisture. Second, it helps active ingredients penetrate the skin.
- Glycerin – when used on skin works as humectant, which is why it attracts moisture onto your skin.
- Carbomer – helps to distribute and suspend the active ingredients in the R-Andro Cream.
- Triethanolamine (TEA) – Helps the water-soluble and oil-soluble ingredients blend better. TEA neutralizes fatty acids and solubilizes oils and other ingredients that are not completely soluble in water.
For best results apply 1 pump of R-ANDRO Cream twice daily (1 pump in AM & 1 pump in PM) to the upper arms, shoulders/traps, thighs or abdominal areas. Ensure the areas are clean and free from excessive hair, avoid showering or swimming for at least 8 hours after application.