What is KSM-66?
The Most Clinically Studied Ashwagandha on the Market
Ixoreal is the industry leader in clinical trials and basic research investigating the effectiveness of ashwagandha. KSM-66 has been evaluated in 22 “Gold Standard” human clinical trials. KSM-66 Ashwagandha is a branded, full-spectrum extract, with the highest concentration of all major root only extracts available on the market today. It is produced using a unique proprietary extraction process, based on “Green Chemistry” principles, without using alcohol or any other chemical solvent.
KSM-66 Ashwagandha has been *clinically proven to:
- Help reduce stress, anxiety, cortisol levels and stress-related food cravings†
- Help promote enhanced memory and cognitive function†
- Help promote endurance, strength, muscle size and muscle recovery rate†
- Help enhance sexual performance health in both men and women, and testosterone in men†
*See all Clinical Studies here: https://ksm66ashwagandhaa.com/clinical-studies/
Award Winning: For several of the factors listed above, KSM-66 was awarded the Sports Nutrition Ingredient of the year, by The NutraIngredients Asia 2018, the recipient of “SFE-Herbal Industry Leader Award” 2016, Frost & Sullivan 2014 “Product Innovation in Botanicals” award, “Best Botanical Ingredient” award for 2013 at Natural Products Expo West and “Innovative Ingredient of the Year” award for 2012 at Panacea.
KSM-66 Strictly Avoids the Use of Leaves
KSM-66 uses only the roots of the ashwagandha plant with absolutely no addition of leaves. Our financial advisors point out that our profits would be far higher if we replaced roots with leaves, given that the price of leaves is often less than 1/15th the price of roots. Despite that, our founders have stood by their basic principle to use roots only. Customers are often curious to know why. To understand our rationale, it helps to know a little about our company. We are a family-owned business founded with the sole mission of supplying the absolute best quality ashwagandha. To be faithful to our mission, we feel it necessary to stay close to mainstream practice and modern scientific evidence. Both in independent clinical trials and in thousands of years of traditional use, the root is the part of the plant that is used predominantly for adaptogenic benefits and internal ingestion. The primary use of leaves traditionally was for topical treatments on the skin for conditions like burns or carbuncles, not internal consumption. The use of the roots is on significantly better scientific foundation in terms of human clinical evidence and period of observation than the use of leaves.†
- Ashwagandha root consumption has been much heavier with much greater opportunity to observe its safety than ashwagandha leaf consumption.
- The predominant majority of published clinical trials today are on the root and not the leaf.
- The coverage of ashwagandha in reference works like the pharmacopoeias is only on the root. These reference works are the United States Pharmacopoeia, the British Pharmacopoeia, the Indian Pharmacopoeia, the Ayurvedic Pharmacopoeia, Indian Materia Medica, the Health Canada monograph and the W.H.O. monograph. The leaf is in fact not even mentioned in any of them for therapeutic use and ingestion.
- Regulatory bodies in some European countries allow only the root of ashwagandha plant and not the leaves.
Given that the leaves are plentiful and easily accessible, what reason would Ayurveda practitioners have to go through all the trouble to dig up the root if not their strong belief that the root is better? The pursuit of the ashwagandha root is notable indeed in Ayurveda. Even the very name of the herb (“ashwa” for horse and “gandha” for smell) is owing to the root which smells like a horse, according to Ayurveda texts.†
KSM-66 is Ixoreal’s ashwagandha extract, created via a process that took 14 years of R&D to develop and refine. KSM-66 is the best ashwagandha extract on the world market today in the sense that it is the highest concentration full-spectrum extract available today. A “full-spectrum” extract is an extract which maintains the balance of the various constituents as in the original herb, without over-representing any one constituent. The ashwagandha herb’s efficacy is believed to be derived from a complex blend of active constituents. All the constituents need to be present in their natural proportions, which is why it is important for an extract to be full-spectrum. However, producing a high concentration full-spectrum extract is technologically very challenging. Only Ixoreal has managed to create a process that surmounts these challenges, and that too only after many years of R&D. The Ixoreal science team sought to introduce to the world the true quintessence of ashwagandha with all its benefits. Convinced that the essence of the ashwagandha root could be extracted without losing its potency, the science team dedicated itself to learning the nuances of plant chemistry and did what no one was able to achieve until then. With `Green Chemistry` processing, they were able to holistically extract all the root essence while preserving its natural healing potency. This proved to be immensely successful.†
KSM-66’s extraction process entails pre-treating the ashwagandha roots with milk. For this reason, it contains milk constituents. Such pre-treatment is consistent with the process described by traditional ayurveda healers and texts. However, the traditional process does not scale up very well. Ixoreal has taken this traditional method and refined it greatly so that it produces high quality ashwagandha in a scalable manner, combining the traditional with the modern. Therein lies Ixoreal’s “secret sauce”, a highly proprietary process that took 14 years to develop and implement. The milk pre-treatment is important in our extraction process because this is in fact what leads to retention of both hydrophilic components and lipophilic components of the raw root, which in turn leads to a full-spectrum extract of such high-potency. For formulators targeting products at consumers who are vegan or for other reasons want to avoid milk, we also have a version of KSM-66 where the milk-pretreatment is skipped: this version of KSM-66 is vegan and milk-free.†
What Is ZMA?
ZMA is a natural mineral supplement made up of zinc, magnesium aspartate, and vitamin B6. Zinc supports your immune system and muscles. Magnesium plays a role in metabolism and muscle health and helps manage sleep. B6 may boost energy. ZMA makers claim that increasing these three nutrients in your system can build muscle strength and stamina, speed muscle recovery, and improve the quality of your sleep. A deficiency in either of these minerals may reduce your production of testosterone, a hormone that affects muscle mass, as well as insulin-like growth factor (IGF-1), a hormone that affects cell growth and recovery. In addition, many athletes may have low zinc and magnesium levels, which can compromise their performance. Lower zinc and magnesium levels may be the result of strict diets or losing more zinc and magnesium through sweat or urination.†
May aid blood sugar control
Zinc and magnesium may help people with diabetes control their blood sugar levels. An analysis of 25 studies in over 1,360 people with diabetes showed that taking a zinc supplement reduced fasting blood sugar, hemoglobin A1c (HbA1c), and post-meal blood sugar levels (6Trusted Source).†
Magnesium may also improve blood sugar control in people with diabetes by improving the body’s ability to use insulin, a hormone that moves sugar from your blood into cells. In fact, in an analysis of 18 studies, magnesium was more effective at reducing fasting blood sugar levels than a placebo in people with diabetes. It also significantly reduced blood sugar levels in those at risk of developing diabetes.†
May help improve your sleep
The combination of zinc and magnesium may improve your sleep quality. Research suggests that magnesium helps activate the parasympathetic nervous system, which is responsible for helping your body feel calm and relaxed. Meanwhile, supplementing with zinc has been linked to improved sleep quality in both human and animal studies. An 8-week study in 43 older adults with insomnia showed that taking a combination of zinc, magnesium, and melatonin — a hormone that regulates sleep-wake cycles — daily helped people fall asleep faster and improved sleep quality, compared to a placebo (33Trusted Source).†
May elevate your mood
Magnesium and vitamin B6, both of which are found in ZMA, may help elevate your mood.One study in approximately 8,900 adults found that those under the age of 65 with the lowest magnesium intake had a 22% higher risk of developing depression. Another 12-week study in 23 older adults showed that taking 450 mg of magnesium daily reduced depression symptoms as effectively as an antidepressant drug. Several studies have linked low blood levels and intakes of vitamin B6 to depression. However, taking vitamin B6 doesn’t appear to prevent or treat this condition.†
5-DHEA has been popular in the life extension crowd since the 1980’s. It’s typically used for its ability to support energy and general well being. More recently higher doses of 5-DHEA have been used to improve body composition due to DHEA’s mild anabolic and thermogenic effects. This makes 5-DHEA an excellent choice for cutting during a calorie deficient diet since 5-DHEA has good muscle sparing properties.†
As a dietary supplement take three (3) capsules per day. Do not use for more than 12 weeks.